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Clinical Inquiries, j Fam Pract. 2007 August;56(8 671-672, jinping Xu, MD, MS, kendra Schwartz, MD, msph. Wayne State University, Detroit, Mich, kristin Hitchcock, MSI, department of Preventive Medicine, when to take diflucan with antibiotics Northwestern University, Chicago, Ill. Sobel JD, Faro S, when to take diflucan with antibiotics Force RW,. Vulvovaginal candidiasis: epidemiologic, diagnostic, and therapeutic considerations. Am J Obstet Gynecol 1998;178:203-211. N Engl J Med 1997;337:1896-1903. Xu J, Sobel. Curr Infect Dis Rep 2003;5:481-487. Sobel JD, Chaim. Vaginal microbiology of women with acute recurrent vulvovaginal candidiasis. J Clin Microbiol 1996;34:2497-2499. Hawes SE, Hillier SL, Benedetti J,. Hydrogen peroxide-producing lactobacilli and acquisition of vaginal infections. J Infect Dis 1996;174:1058-1063. Watson MC, Grimshaw JM, Bond CM, Mollison J, Ludbrook. Oral versus intra-vaginal imidazole and triazole antifungal treatment of uncomplicated vulvovaginal candidiasis (thrush). Cochrane Database Syst Rev 2001 1 CD002845.-. Sobel JD, Wiesenfeld HC, Martens M,. Maintenance fluconazole therapy for recurrent vulvovaginal candidiasis. N Engl J Med 2004;351:876-883. Spinillo A, Colonna L, Piazzi G, Baltaro F, Monaco A, Ferrari. Managing recurrent vulvovaginal candidiasis. Intermittent prevention with itraconazole. J Reprod Med 1997;42:83-87. Pirotta when to take diflucan with antibiotics M, Gunn J, Chondros P,. Effect of lactobacillus in preventing postantibiotic vulvovaginal candidiasis: a randomised controlled trial. Pappas when to take diflucan with antibiotics PG, Rex JH, Sobel JD,. Guidelines for treatment of candidiasis. Clin Infect Dis 2004;38:161-189. Evidence-based answer Oral and intravaginal antifungals for the treatment of uncomplicated vulvovaginal candidiasis (VVC) have similar effectiveness (strength of recommendation SOR: A, systematic review). However, no randomized controlled trials (RCTs) have addressed treatment options for patients taking antibiotics. Oral antifungals are contraindicated in pregnancy.
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